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bs 1683r  (Bioss)


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    Structured Review

    Bioss bs 1683r
    Bs 1683r, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bs 1683r/product/Bioss
    Average 94 stars, based on 3 article reviews
    bs 1683r - by Bioz Stars, 2026-02
    94/100 stars

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    Image Search Results


    Risk model for predicting the survival status of NB. (A) Significance and hazard ratio values of stage-related DEGs in univariate Cox regression. All of the 55 candidate genes passed the PH test. (B) The LASSO model has the lowest error rate and yielded four prognostic genes, including CDKN3 , PCLAF , PRKACB , and CNR1 . (C, D) The distribution of risk scores, the association between risk scores and OS, and the mRNA expression of the four genes. (E) K–M curves showed dramatically higher concurrent survival rates of patients in the low-risk cohort than those in the high-risk group. (F) The ROC curve of the predictive performance of the four genes.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models

    doi: 10.3389/fcell.2025.1502380

    Figure Lengend Snippet: Risk model for predicting the survival status of NB. (A) Significance and hazard ratio values of stage-related DEGs in univariate Cox regression. All of the 55 candidate genes passed the PH test. (B) The LASSO model has the lowest error rate and yielded four prognostic genes, including CDKN3 , PCLAF , PRKACB , and CNR1 . (C, D) The distribution of risk scores, the association between risk scores and OS, and the mRNA expression of the four genes. (E) K–M curves showed dramatically higher concurrent survival rates of patients in the low-risk cohort than those in the high-risk group. (F) The ROC curve of the predictive performance of the four genes.

    Article Snippet: After being blocked by 5% bovine serum albumin (BSA) for 2 h at room temperature, the membranes were incubated with one of the following primary rabbit antibodies at 4°C overnight: CNR1 , diluted at 1:1000, bs-1683R, Bioss; PRKACB , 1:1000, AF7746, Affinity Biosciences; CDKN3 , 1:1000, DF6791, Affinity Biosciences; PCLAF, 1:1000, 81533, Cell Signaling Technology.

    Techniques: Expressing

    Verification of mRNA expression of DEGs. The mRNA expressions of CDKN3 and PCLAF were significantly upregulated and that of PRKACB was downregulated at the advanced stage. No significant change was observed in the CNR1 mRNA level.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models

    doi: 10.3389/fcell.2025.1502380

    Figure Lengend Snippet: Verification of mRNA expression of DEGs. The mRNA expressions of CDKN3 and PCLAF were significantly upregulated and that of PRKACB was downregulated at the advanced stage. No significant change was observed in the CNR1 mRNA level.

    Article Snippet: After being blocked by 5% bovine serum albumin (BSA) for 2 h at room temperature, the membranes were incubated with one of the following primary rabbit antibodies at 4°C overnight: CNR1 , diluted at 1:1000, bs-1683R, Bioss; PRKACB , 1:1000, AF7746, Affinity Biosciences; CDKN3 , 1:1000, DF6791, Affinity Biosciences; PCLAF, 1:1000, 81533, Cell Signaling Technology.

    Techniques: Expressing

    Verification of protein expression of DEGs. Immunohistochemistry (IHC) and Western blot (WB) analysis of CDKN3 , PCLAF , PRKACB , and CNR1 expression in low-risk versus high-risk NB tumor tissue samples. (A) Representative IHC images of these four genes in tumor tissues. Scale bar: 100 μm, (B) Western immunoblots. GAPDH was used to normalize. The expressions of CDKN3 and PCLAF were significantly upregulated and that of PRKACB was downregulated at the advanced stage of NB, compared with the early stage, with statistical significance indicated (*p < 0.05, **p < 0.01).

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models

    doi: 10.3389/fcell.2025.1502380

    Figure Lengend Snippet: Verification of protein expression of DEGs. Immunohistochemistry (IHC) and Western blot (WB) analysis of CDKN3 , PCLAF , PRKACB , and CNR1 expression in low-risk versus high-risk NB tumor tissue samples. (A) Representative IHC images of these four genes in tumor tissues. Scale bar: 100 μm, (B) Western immunoblots. GAPDH was used to normalize. The expressions of CDKN3 and PCLAF were significantly upregulated and that of PRKACB was downregulated at the advanced stage of NB, compared with the early stage, with statistical significance indicated (*p < 0.05, **p < 0.01).

    Article Snippet: After being blocked by 5% bovine serum albumin (BSA) for 2 h at room temperature, the membranes were incubated with one of the following primary rabbit antibodies at 4°C overnight: CNR1 , diluted at 1:1000, bs-1683R, Bioss; PRKACB , 1:1000, AF7746, Affinity Biosciences; CDKN3 , 1:1000, DF6791, Affinity Biosciences; PCLAF, 1:1000, 81533, Cell Signaling Technology.

    Techniques: Expressing, Immunohistochemistry, Western Blot